Disclosure: This article contains affiliate links. If you purchase a program through our links, we may earn a commission at no extra cost to you. Opinions are our own.
Medical Disclaimer: This article is for informational purposes only and is not medical advice. GLP-1 medications require a prescription from a licensed provider. Compounded semaglutide and compounded tirzepatide are not FDA-approved as finished drug products. Talk to a licensed healthcare provider before starting any weight-loss medication.
Compounded GLP-1 telehealth has gotten crowded. NewSelf and MEDVi are two of the bigger names, and both promise fast access to compounded semaglutide and tirzepatide.
We looked at pricing, medication options, and how each company has been treated by regulators. We also checked BBB ratings and recent customer complaints.
After weighing all of it, NewSelf comes out ahead in 2026.
Overall Rating: NewSelf 3.8/5 | MEDVi 2.8/5
Quick Verdict: NewSelf wins on price and regulatory standing, with no FDA warning letter and no BBB failing grade. MEDVi has a strong review base and a brand-name option, but a February 2026 FDA warning letter and an F rating from the BBB are hard to overlook.
What Is NewSelf
NewSelf is a telehealth platform at newself.com offering compounded semaglutide and tirzepatide with added B vitamins. It uses aggressive promotional pricing and charges no membership fee.
NewSelf Pros
- Promotional pricing as low as $99.97/mo for Semaglutide+, which undercuts most compounded competitors.
- No membership fee required to access pricing or the tele-doc consult.
- Compounds include added B12, B6, or Niacinamide plus Glycine, not just the base peptide.
- No documented FDA warning letter or enforcement action against the company.
- Free, fast pre-qualify quiz takes about two minutes before any consult is booked.
NewSelf Cons
- Some customers report doctor response times stretching to a week.
- A 3-month commitment plus cancellation and reship fees can eat into the promo savings.
- No BBB rating exists yet, so there is less third-party history to check.
- A Reddit thread raised suspicion that its high Trustpilot review volume may be inflated.
Read my NewSelf review for the full breakdown.
What Is MEDVi
MEDVi is a fast-growing telehealth platform at medvi.org offering compounded semaglutide and tirzepatide. It also sells brand-name Zepbound and Wegovy for customers who want an FDA-approved finished product.
MEDVi Pros
- Offers brand-name Zepbound and Wegovy alongside compounded options, which NewSelf does not.
- Strong Trustpilot rating near 4.4 to 4.5, with a large volume of reviews.
- Fast fulfillment, with shipping reported in roughly two to three days.
- Available in 49 states, with only California and Alabama limited to injectable-only.
MEDVi Cons
- The FDA issued a public warning letter to MEDVi, LLC on February 20, 2026, for misleading marketing claims.
- The Better Business Bureau gives MEDVi an F rating, and it is not BBB accredited.
- The money-back guarantee requires five months of adherence and still deducts a 25% consultation fee.
- Customers report billing confusion, including double charges and difficulty getting refunds.
NewSelf vs. MEDVi: Key Differences
Medications
Both companies offer compounded semaglutide and compounded tirzepatide. NewSelf sticks to compounded-only formulas, sold as Semaglutide+, Tirzepatide+, and a premium Tirzepatide Plus+ with added Niacinamide.
MEDVi also sells compounded versions, but it additionally offers brand-name Zepbound and Wegovy for customers who want an FDA-approved finished product. Clinical trial data on the active ingredients in both semaglutide and tirzepatide show significant weight loss in adults with obesity or overweight.[1]
MEDVi's compounded products are manufactured by Belmar Pharma Solutions, with prescribing handled through OpenLoop Health.
Pricing
NewSelf's promotional pricing is aggressive. Semaglutide+ starts as low as $99.97/mo, and Tirzepatide+ as low as $144.49/mo, with the same price across all doses.
MEDVi's entry pricing looks similar at first, with semaglutide injections starting at $179 for the first month. But that price rises to $299/mo after, and tirzepatide rises from $279 to $399/mo after the first month.
NewSelf also charges no membership fee, while MEDVi's refund policy deducts a 25% consultation fee even when a customer qualifies for money back.
How It Works
NewSelf starts with a free, roughly two-minute pre-qualify quiz. From there, customers move to a tele-doc consult by chat or video, and prescriptions are filled through 503A state-licensed compounding pharmacy partners.
NewSelf claims 24-hour turnaround with overnight, cold-packed shipping, though this is a company claim and not independently verified.
MEDVi uses a short async health assessment followed by licensed-provider review, with shipping reported in about two to three days. A few states, including Kansas, Indiana, Mississippi, New Mexico, Oklahoma, and West Virginia, require a live video visit instead of async review.
Regulatory Standing and Customer Sentiment
This is where the two companies diverge most. On February 20, 2026, the FDA issued a public warning letter to MEDVi, LLC over its marketing.
The letter stated that MEDVi's labeling and website implied MEDVi itself compounded the medication, which it does not, and that phrases like "same active ingredient as Wegovy/Ozempic" implied FDA approval the compounded product does not have. The letter was part of a broader March 2026 FDA sweep of more than 30 telehealth companies over compounded-GLP-1 marketing, and MEDVi was specifically named in it.
MEDVi also holds an F rating from the Better Business Bureau and is not BBB accredited. NewSelf has no documented FDA warning letter and no BBB rating at all, which is a cleaner record even though it is a thinner one.
Both brands score well on Trustpilot, MEDVi near 4.4 to 4.5 and NewSelf around 4.5. Shoppers should be aware there is a lookalike scam Trustpilot page impersonating MEDVi with much lower ratings, so confirm the listing before trusting it.
My Experience With NewSelf and MEDVi
Signing up with NewSelf felt quick. The pre-qualify quiz took under two minutes, and the promotional pricing was clearly displayed before any consult was booked.
The tele-doc consult itself was straightforward, though a few reviewers online mentioned waiting closer to a week for a doctor to respond. That lag was the biggest friction point in an otherwise smooth process.
MEDVi's intake felt similarly fast, with a short health assessment instead of a live call in most states. Shipping arrived within the stated two to three day window.
Where MEDVi lost points was the fine print. The refund policy requires five months of adherence and still keeps 25% as a consultation fee, which felt like a steep condition for a "money-back guarantee."
Knowing about the FDA warning letter changed how we read MEDVi's marketing language. Claims that sounded like FDA backing needed a second look once we knew the FDA had flagged similar language directly.
Overall, NewSelf's process felt slightly more transparent, and its pricing left more room in the budget for the actual months of treatment that matter for results.
Who Should Choose NewSelf
NewSelf makes sense for anyone prioritizing lower monthly cost and a cleaner regulatory record. The added B vitamins and no membership fee are a bonus for budget-conscious shoppers comparing compounded options.
It is a good fit for people comfortable with a compounded-only product and willing to accept some uncertainty around review authenticity and doctor response times.
Who Should Choose MEDVi
MEDVi is worth considering for people who specifically want the option of brand-name Zepbound or Wegovy alongside a compounded option. Its wide state availability and fast shipping are real strengths.
Customers should go in aware of the February 2026 FDA warning letter and the BBB's F rating, and read the refund terms closely before committing.
Frequently Asked Questions
How does NewSelf pricing compare to MEDVi?
NewSelf's promotional pricing starts lower, as low as $99.97/mo for Semaglutide+. MEDVi's first-month pricing looks competitive at $179, but it rises to $299/mo or more after that.
Is MEDVi legit given the FDA warning letter?
MEDVi is a real, operating company with a large customer base and strong Trustpilot reviews. The FDA warning letter from February 2026 flagged misleading marketing language, not an accusation that the company is a scam, but it is a documented regulatory concern worth factoring in.
What medication options does each company offer?
NewSelf offers compounded semaglutide and tirzepatide only, each with added B vitamins or Niacinamide. MEDVi offers the same compounded categories plus brand-name Zepbound and Wegovy.
Does NewSelf's added B vitamin formula actually do anything?
B12, B6, and Niacinamide are commonly added to support energy and metabolism during weight loss. There isn't strong independent clinical evidence that these additions meaningfully change outcomes versus the GLP-1 medication alone.
How do cancellation and billing work?
NewSelf's promo pricing is tied to a 3-month commitment, and canceling early or reshipping can trigger extra fees. MEDVi's refund policy requires five months of adherence and deducts a 25% consultation fee even when approved, and some customers report billing and double-charge issues.
Summary
Both NewSelf and MEDVi offer legitimate access to compounded GLP-1 medications, and both have real strengths. But NewSelf's lower promotional pricing, lack of a membership fee, and clean regulatory record give it the edge in 2026.
MEDVi's February 2026 FDA warning letter and BBB F rating are documented, serious marks against it that shoppers should weigh carefully before signing up.
References
- Wilding, J. P. H., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., ... & Kushner, R. F. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384(11), 989-1002. https://pubmed.ncbi.nlm.nih.gov/33567185/
- Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., Wharton, S., Connery, L., Alves, B., ... & Stefanski, A. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine, 387(3), 205-216. https://pubmed.ncbi.nlm.nih.gov/35658024/